Key Model for Alzheimer's Drug Development
Alzheimer's disease, or dementia, refers to a persistent disorder of higher neurological activity, which simply means that memory, thinking, analytical judgment, visuospatial recognition, and mood are impaired in the absence of conscious impairment.We have established a stable model of Alzheimer's disease, which is suitable for preclinical Alzheimer's disease drug research and new drug evaluation.
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Model classification | Model Name | Animal species |
Alzheimer's disease | APP/PS1 mouse model of Alzheimer's disease | Mice |
5xFAD mouse model of Alzheimer's disease | Mice | |
3xTg mouse model of Alzheimer's disease | Mice | |
Model of Alzheimer's disease induced by high-fat, high-cholesterol feeds | Rabbits | |
Model of diffuse blood-brain barrier damage induced by high-fat and high-cholesterol feeds |
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Alzheimer's disease model induced by aluminum chloride + D-aminogalactosamine (D-Gal) | Rats |