Key Model for Drug Development of Metabolic Nephropathy
Metabolic nephropathy is divided into two main types: diabetic nephropathy and hyperuricemia nephropathy.We have established stable models of diabetic nephropathy and hyperuricemia nephropathy, which are suitable for the research of drugs for preclinical metabolic nephropathy and new drug evaluation.
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Model classification | Model Name | Animal species |
Metabolic nephropathy | Streptozotocin (STZ) + high-fat diet-induced diabetic nephropathy model | Rats |
Model of obesity nephropathy induced by high-fat feed alone | Mice | |
Model of metabolic nephropathy induced by high-fat and high-cholesterol feeds |