Key Model for Vomiting Drug Development
Vomiting is a common clinical symptom that occurs when the contents of the stomach or intestines are expelled from the body through the esophagus and out of the mouth by a forceful contraction of the stomach. Frequent and severe vomiting can cause some damage to the body, such as water and electrolyte disorders, malnutrition, and esophageal and gastric injury.
We have established a stable model of cisplatin-induced emesis and a model of GLP-1RA-induced emesis, which are suitable for the study of drugs with preclinical emesis and the evaluation of new drugs.
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Model classification | Model Name | Animal species |
vomit | Model of cisplatin-induced vomiting | Rats |
Model of GLP-1RA-induced vomiting | Rats |
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