Key Model for Drug Development of Silicosis
Pneumoconiosis, also known as pneumoconiosis, is a disease caused by long-term inhalation of inorganic mineral dust and characterized by diffuse nodular or lattice fibrosis of lung tissue. The cause is often attributed to occupational or environmental factors such as silica dust, asbestos dust or carbon black dust. Pneumoconiosis is divided into many types, such as silicosis, coal workers' pneumoconiosis, graphite pneumoconiosis, and asbestosis. Pathogenesis is related to dust particle size, dust concentration, exposure time and other factors. Pneumoconiosis is one of the common and major occupational diseases in China.We have established a stable silica-induced silicosis model, which is suitable for the study of drugs for preclinical silicosis and the evaluation of new drugs.
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Model classification | Model Name | Animal species |
Silicosis | Silicon dioxide-induced silicosis model | Mice，rats |