Product catalog
contact us

    KCI BioTech (Suzhou) Inc.
    Tel:0512-69998806
    Ministry of Commerce:0512-69998806-8012
    BD:
    East and South China:Ms. Gu 15378638068
    North China, East China:Mr. Han 18914988667
    Central and Western regions: Ms. Xiang 15828112963
    Project Management Department:0512-69998806-8022
    Tumor business:0512-69998806-8058
    Non tumor business:0512-69998806-8026
    Pathogenic microorganism business:0512-69998806-8037
    Integrated Service Platform:0512-69998806-8022
    Address: Building A2, Xinyang Industrial Park, No. 8 Yanghua Road, Suzhou Industrial Park

In vivo PK study

       In in vivo pharmacokinetic (PK) experiments, the modes of administration include, but are not limited to intravenous, oral, administration, intraperitoneal injection,intramuscular injection, subcutaneous injection, ventricular administration, intrathecal injection, nasal administration, and tracheal administration. The sampling time point can be set at 24 hours or more according to the characteristics of the compound and the specific requirements of the project, to ensure a comprehensive evaluation of the dynamic changes of the drug in the body.

Our services

experiment

describe

Species and genus

result

Conventional single dose

pharmacokinetics

Single dose administration for each route of administration;
Collect 8-10 sampling time points before and after administration;
Quantitative analysis using LC/MS/MS method;
WinNolin8.2 software calculates PK parameters;
Calculate the absolute bioavailability after
extravascular administration.

Mouse, rat, rabbit, dog, monkey

Medication time curve graph
Basic PK parameters
Bioavailability
research report

Multi dose pharmacokinetics

Single dose administration for each route of administration;
Collect 8-10 sampling time points before and after administration;
Quantitative analysis using LC/MS/MS method;
WinNolin8.2 software calculates PK parameters;
Calculate the absolute bioavailability after
extravascular administration.

Mouse, rat, rabbit, dog, monkey

Medication time curve graph
Basic PK parameters
PK linear judgment
Bioavailability
research report

Comparative pharmacokinetics

Test formulation and reference formulation;
Collect 8-10 sampling time points before and after administration;
Quantitative analysis using LC/MS/MS method;
WinNolin8.2 software calculates PK parameters;
Calculate the absolute bioavailability after
extravascular administration.

Mouse, rat, rabbit, dog, monkey

Medication time curve graph
Basic PK parameters
Significant difference judgment
Bioavailability
research report




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