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    KCI BioTech (Suzhou) Inc.
    Tel:0512-69998806
    Ministry of Commerce:0512-69998806-8012
    BD:
    East and South China:Ms. Gu 15378638068
    North China, East China:Mr. Han 18914988667
    Central and Western regions: Ms. Xiang 15828112963
    Project Management Department:0512-69998806-8022
    Tumor business:0512-69998806-8058
    Non tumor business:0512-69998806-8026
    Pathogenic microorganism business:0512-69998806-8037
    Integrated Service Platform:0512-69998806-8022
    Address: Building A2, Xinyang Industrial Park, No. 8 Yanghua Road, Suzhou Industrial Park

       KCI·KMQ has established an anti infection research and service platform with dual qualifications of BSL2 and ABSL2. The BSL-2 laboratory covers an area of approximately 200m ² and includes cells, viruses, and bacteria; The experimental area of ABSL2 is about 1000m ², including 300m ² for small animal laboratory and 700m ² for large animal laboratory. This platform is equipped with a professional operation and technical team, including senior scientists, dedicated laboratory personnel, dedicated veterinarians, and a QA management system. The staff have received special training in professional operations, obtained relevant qualifications, and carried out related work under the guidance and management of scientists with experience in anti infection research and development.

       After nearly 2 years of internal research and development and external services, this platform has completed the filing of more than 70 pathogenic microorganisms, successfully established more than 20 animal models of viral and bacterial fungal infections, and has cooperated with more than 20 new drug research and development enterprises in the fields of human vaccines and anti infective drugs, animal vaccines and anti infective drugs, etc., to assist in the development and application of preclinical drugs. At present, the main businesses involved include:

       Human vaccines and anti infective drugs, veterinary vaccines and anti infective drugs

(1)In vitro anti infective efficacy test:

Antiviral activity - EC50/CC50 detection; MIC drug sensitivity test; FIC measurement; Effects of biological characteristics, etc.

(2)Immunogenicity testing of vaccines in vivo: neutralization test, hemagglutination inhibition test, cellular immunity test, etc;

(3)Animal protective testing against viruses: vaccines, antiviral drugs;

(4)Infectious animal testing.
Human vaccine and anti infective drug service plat Click to enter the model catalog
Veterinary vaccine and anti infective drug service Click to enter the model catalog
BSL-2/ABSL-2 Laboratory Click to enter the model catalog

animal model

List of Animal Model Information for KCI KMQ Biological Anti Infection Service

classification

name

subtype

model

Animal species

mice

rat

cotton mouse

guinea pig

pig

cat

ferret

rabbit

virus

respiratory syncytial virus

A2/ 9320/ 18537

Attack on Poison Model

 

 

 

 

 

 

HBV

 

AAV-HBV1.3 infection model

 

 

 

 

 

 

 

flu virus

H1N1/H3N2
B Victoria
B Yamagata

Attack on Poison Model

 

 

 

 

 

 

Human herpesvirus 2 

(HSV-2)

MS

Reproductive tract infection 

model

 

 

 

 

 

 

Herpes zoster virus 

(VZV)

Oka

Neuralgia/Skin Herpes

 

 

 

 

 

 

Feline infectious 

peritonitis virus

FCoV II

Cat transmitted abdominal 

infection model

 

 

 

 

 

 

 

Rabbit Papilloma Skin 

Disease Model

NA

Rabbit CRPV virus skin 

papilloma

 

 

 

 

 

 

 

Porcine Blue Ear Virus 

(PRRSV)

High fever type

Porcine Reproductive and 

Respiratory Syndrome 

Virus Infection Model

 

 

 

 

 

 

 

bacteria

Staphylococcus aureus

Seattle 1945

Skin wound infection model

 

 

 

 

 

 

 

Septicemia model

 

 

 

 

 

 

 

Escherichia Coli

Seattle 1946

Septicemia model

 

 

 

 

 

 

 

enterobacter cloacae

Clinical strain

Model of thigh muscle infection

 

 

 

 

 

 

 

Acinetobacter baumannii

Clinical strain

Pneumonia model

 

 

 

 

 

 

 

Model of thigh muscle infection

 

 

 

 

 

 

 

klebsiella pneumoniae

C122

Infectious pneumonia model

 

 

 

 

 

 

 

Pseudomonas 

aeruginosa

ATCC9027

Infectious model of pneumonia

 

 

 

 

 

 

 

Septicemia model

 

 

 

 

 

 

 

Model of thigh muscle infection

 

 

 

 

 

 

 

fungus

Candida albicans

3147

Vaginitis model

 

 

 

 

 

 

 

Septicemia model

 

 

 

 

 

 

 

Pneumonia model

 

 

 

 

 

 


Service Items

experiment

Isolation and cultivation of bacteria/fungi/viruses

In vitro antiviral CC50 and EC50 testing

In vitro antimicrobial susceptibility test

Minimum inhibitory concentration (MIC) 

determination

1. Micro broth dilution method

2. Paper amplification method

FIC assay chessboard method combined with antibacterial ability determination

Influence of biological characteristics

1. Growth curve

2. Sports force

3. Biofilm

4. Adhesive invasion

Evaluation of vaccine immunogenicity

Humoral immune evaluation

1. Combining IgG antibodies and detecting different subtypes

2.Neutralization test/hemagglutination inhibition test

Cellular immune evaluation

ELISOPT IFN - γ/IL-2/IL-4/IL-6 detection

Flow detection - CD4+\ CD8+\ IFN - γ+\ TNF - α+\ IL-2+

\ IL-4+\ IL-6+and other detection methods

Anti toxic protective experiment

Evaluation of therapeutic anti infective drugs