Key Model for Drug Development of Metabolic Nephropathy
Metabolic nephropathy is divided into two main types: diabetic nephropathy and hyperuricemia nephropathy.We have established stable models of diabetic nephropathy and hyperuricemia nephropathy, which are suitable for the research of drugs for preclinical metabolic nephropathy and new drug evaluation.
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Disease name | Model name | Animal species |
Metabolic nephropathy | Diabetes nephropathy model induced by streptozotocin (STZ)+high-fat diet | mouse, rat |
Obese nephropathy model induced by high-fat diet alone | mouse | |
Model of metabolic nephropathy induced by high-fat and high-cholesterol feeds | rabbit |
Case sharing
Metabolic nephropathy model
