Key model for drug development of ventricular tachycardia
Ventricular tachycardia (VT) refers to a rapid arrhythmia that occurs in the bundle branches, myocardial conduction fibers, and ventricular muscles below the bifurcation of the His bundle. VT can originate in the left and right ventricles, and its frequency often exceeds 100 beats per minute during persistent episodes. It can also deteriorate the hemodynamic state and may transform into ventricular flutter, ventricular fibrillation, leading to sudden cardiac death, requiring active treatment.
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Model classification | Model Name | Animal species |
Ventricular tachycardia | Barium chloride-induced ventricular tachycardia | Rat, rabbit |
Adrenaline-induced ventricular tachycardia | Rabbit |