Evaluate Key Aspects of Acute Myocardial Infarction
Acute myocardial infarction (AMI) is myocardial necrosis caused by acute or persistent coronary ischemia, with increase of serum myocardial enzyme and characteristic abnormal ECG. It can be complicated by arrhythmia, shock or cardiac failure and cause sudden death. Clinical AMI often cause intense and long-lasting post-sternal pain, these symptoms cannot be completely relieved by rest or nitrate drugs. AMI often can be life-threatening.
KCI provides highly translatable and stable in vivo models for AMI to help preclinical new drug development.
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Item | Model setting | Animals |
Acute myocardial infarction models | Ischemia reperfusion model | Rodent, Rabbit, Pig, Dog, NHP |
Permanent ischemia model | Rodent, Rabbit, Pig, Dog, NHP |
案例分享
大鼠急性心梗模型
Rat AMI model
兔急性心梗模型
Rabbit AMI model
猪急性心梗模型
Pig AMI model
非人灵长类动物急性心梗模型
NHP AMI model