Evaluate Key Aspects of Cardiac Failure
Heart failure (HF) is a disease caused by a malfunction of the heart's pumping function, resulting in the heart's inability to meet the basic metabolic needs of the entire body. Frequent triggers include myocardial infarction, cardiomyopathy, and myocarditis. In acute heart failure, or acute exacerbation of chronic heart failure, patients may experience acute pulmonary edema, shock, syncope or even cardiac arrest, which can be life-threatening.We have established a stable model of heart failure caused by different triggers, which is suitable for preclinical research and new drug evaluation of drugs for the treatment of heart failure.
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Disease name | Model name | Animal species |
| heart failure | Heart Failure Model Induced by Myocardial Infarction | mouse, rat, rabbit, dog, pig, non-human primate |
| Aortic arch constriction-induced heart failure model | mouse, rat, rabbit,cat | |
| Heart failure model induced by ascending aortic constriction | rat, rabbit, dog | |
| Superior vena cava - common carotid artery AV-shunt induced total heart failure model | rabbit, dog | |
| Right heart failure model induced by abdominal aortic constriction | rat, rabbit, dog, non-human primate | |
| Heart failure model induced by pulmonary aortic constriction | rat | |
| Acetic deoxycorticosterone (DOCA)+high salt induced hypertension induced heart failure model | rat | |
| Dahl salt sensitive rats+high salt induced hypertension induced heart failure model | rat | |
| Hypertension induced heart failure model caused by renal artery stenosis | rat,dog, non-human primate | |
| High fat diet induced heart failure model | mouse,hamster,rabbit | |
| Doxorubicin induced heart failure model | mouse, rat, rabbit, dog | |
| Db/db mice + high-fat and high-cholesterol diet-induced heart failure model with reduced ejection fraction | mouse | |
| DIO mice - induced heart failure model with preserved ejection fraction | mouse | |
| ZDF rats + HFD - induced heart failure model with preserved ejection fraction | rat | |
| Naturally aging mice - induced model of heart failure with preserved ejection fraction | mouse |
Case sharing
Heart Failure Model Induced by Myocardial Infarction in Rats
Heart Failure Model Induced by Myocardial Infarction in New Zealand Rabbits
Heart failure model induced by myocardial infarction in non-human primates
Heart Failure Model Induced by Myocardial Infarction in Dogs
Heart failure model induced by ascending aortic constriction (AAB) in rats
Heart failure model induced by abdominal aortic constriction in rats
Rat model of heart failure induced by pulmonary aortic constriction (PAB)
Rat model of hypertension induced heart failure induced by deoxycorticosterone acetate (DOCA)+high salt
Dahl salt sensitive rats+high salt induced hypertension induced heart failure mode
Canine renal artery stenosis induced hypertension induced heart failure model
Rat model of heart failure induced by doxorubicin