Key model for drug development of subacute and chronic renal failure
Chronic kidney disease (CKD) has become one of the important diseases related to the health of people around the world, especially in the stage of end renal failure, its severe complications Renal anemia is closely related to cardiovascular disease, the rapid deterioration of renal function and the decline of quality of life .
KCI's research team has extensive experience in urinary system models and has established a stable model to help you deal with the challenges of drug development in the field of urinary system diseases and meet your new drug development requirements.
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Disease | Method | Animals |
Chronic kidney injury model | 5/6 nephrectomy model | Rodents, NHP |
2/3 renal infarction model (one side nephrectomy, the other side renal artery ligation) | Rodents, NHP |
Renal tubular toxicity (adenine toxicity) model | Rodents |
案例分享
5/6肾切除模型5/6 nephrectomy model
腺嘌呤诱导的慢性肾衰模型Adenine induced chronic renal failure model