Key models for drug development in hyperlipidemia
Hyperlipidemia, also known as hyperlipidemia or dyslipidemia, usually refers to elevated plasma triglycerides and/or total cholesterol, elevated LDL cholesterol, and decreased HDL cholesterol. Hyperlipidemia carries the risk of complicating diseases such as coronary heart disease and cerebrovascular disease.We have established a stable model of hyperlipidemia, which is suitable for preclinical research and new drug evaluation of drugs for hyperlipidemia.
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Disease name | Model name | Animal species |
Hyperlipidemia | A high-fat diet induced hyperlipidemia model | mouse |
A high-fat and high cholesterol diet induced hyperlipidemia model | mouse, hamster, rabbit, dog, non-human primates |
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HFD-CHOL induced hamster hyperlipidemia model
