Key Model for Drug Development of Thyroiditis
Thyroiditis, a disease that produces inflammatory changes due to destruction or necrosis of the follicular structure of the thyroid gland. Common types include Hashimoto's thyroiditis, atrophic thyroiditis, painless thyroiditis, and postpartum thyroiditis. Symptoms are variable and may include localized symptoms such as enlargement and pain in the thyroid gland, as well as systemic symptoms such as hyperthyroidism or hypothyroidism caused by changes in the function of the thyroid gland.The clinical manifestations of thyroiditis vary, with the overall manifestations being localized symptoms such as thyroid enlargement and pain and systemic symptoms such as hyperthyroidism and hypothyroidism caused by changes in thyroid function. Treatment is mainly based on drugs.
We have established a stable thyroiditis model, which is suitable for preclinical drug research and new drug evaluation.
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Model classification | Model Name | Animal species |
Thyroiditis | Inflammation of Hashimoto's thyroid in SD rats induced by porcine thyroglobulin pTg | Rat |
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